Advancing Bladder Preservation: Biomarkers, Decision-Making, and Therapy (2020)

Baltimore, MD US
March 6, 2020 to March 7, 2020

Johns Hopkins Greenberg Bladder Cancer Institute and American Urological Association Translational Research Collaboration

“Advancing Bladder Preservation: Biomarkers, Decision-Making and Therapy” is the third annual translational research collaboration co-sponsored by the Johns Hopkins University Greenberg Bladder Cancer Institute and American Urological Association. This year’s meeting will be held on March 6-7, 2020 at the Johns Hopkins East Baltimore Medical Campus in Baltimore, Maryland. The meeting will be a two-day workshop focused on alternatives to surgical removal of the bladder (radical cystectomy) for patients with muscle-invasive disease. The biological determinants of sensitivity and resistance to radiation therapy-based bladder preservation are unknown and the field lacks biomarkers that could be used for patient selection. There are candidate biomarkers for bladder preservation following treatment with neoadjuvant cisplatin-based chemotherapy, and the meeting will provide a timely opportunity to review the status of ongoing validation studies.

    Program Planning Committee

    • David McConkey, PhD (Chair) - Johns Hopkins University Greenberg Bladder Cancer Institute
    • Trinity Bivalacqua, MD, PhD - Johns Hopkins Hospital
    • Peter Black, MD - University of British Columbia
    • Jason Efstathiou, MD, PhD - Massachusetts General Hospital
    • Yair Lotan, MD - UT Southwestern
    • Arlene Siefker-Radtke, MD - MD Anderson Cancer Center
    • Phuoc Tran, MD, PhD - Johns Hopkins School of Medicine

    Course Registration Fees

    The registration deadline is February 24, 2020.

     AUA MemberNon-Member
    MD/Urologist$200$250
    PhD Research Scientist$200$250
    Resident, Fellow, Trainee, or Student$150$175
    Industry Representative*$450$450

    *For exhibit/promotional opportunities, please contact Keith Price at kprice@AUAnet.org or at 410-689-3749.

    Target Audience

    • Urologists
    • Research scientists
    • Clinical and research faculty
    • Clinical and postdoctoral fellows
    • Residents
    • Medical and graduate students
    • Industry representatives from companies with vested interests in bladder cancer diagnosis and therapies

    Learning Objectives

    At the conclusion of this activity, participants will be able to:

    1. Describe the state of the science in biomarker identification and validation
    2. Understand the potential role of hypoxia modulation in optimization of therapy
    3. Describe the relevant surgical and clinical variables associated with outcomes
    4. Understand patient perspectives
      Course summary
      Course opens: 
      12/02/2019
      Course expires: 
      03/07/2023
      Event starts: 
      03/06/2020 - 2:00pm
      Event ends: 
      03/07/2020 - 3:10pm
      Price:
      $250.00
      Rating: 
      0

      *agenda updates will be posted as they become available

      Friday, March 6, 2020

      2:00 PMArrival, Registration, Light Lunch
      2:30 PMWelcome, Opening Remarks, Goal Setting

      David McConkey, PhD
      Johns Hopkins Greenberg Bladder Cancer Institute

       

      Aria Olumi, MD
      AUA Research Chair; Beth Israel Deaconess Medical Center and Harvard Medical School

       

      Carolyn Best, PhD
      AUA Research Director

      2:40 PMPatient Perspectives Panel: Lived Experience with or without Bladder Preservation

      Moderator: Stephanie Chisolm, PhD
      Bladder Cancer Advocacy Network

      3:40 PMDiscussion, Q&A 
      4:10 PMBreak 
      4:25 PMSetting the Stage: Current Criteria for Bladder Preservation, Disqualifiers, and Other Considerations

      Moderator:
      Jason Efstathiou, MD, DPhil
      Massachusetts General Hospital

      4:50 PMSpeaker Panel: Targeting Barriers to Wider Use of Trimodal Therapy

      Seth Lerner, MD
      Baylor College of Medicine

       

      Leslie Ballas, MD
      University of Southern California

       

      TBD

      5:35 PMComparison of Costs of Radical Cystectomy vs. Trimodal Therapy for Patients with Localized Muscle-Invasive Bladder Cancer

      Stephen B. Williams, MD
      The University of Texas Medical Branch at Galveston

      6:00 PMKEYNOTE: Breaking Down Barriers in Knowledge Translation

      Anna Gagliardi, PhD
      University of Toronto

      6:10 PMDiscussion, Q&A 
      6:30 PMNetworking Reception and Dinner 
      8:00 PMAdjourn 

      Saturday, March 7, 2020

      7:30 AMBreakfast and Morning Registration 
      8:00 AMOpening, Recap from Previous Day, and Goal Setting

      Peter Black, MD
      University of British Columbia

      8:10 AMSession 2: Surgical Issues - Moderator's Introduction

      Moderator:
      Seth Lerner, MD
      Baylor College of Medicine

      8:15 AMStandardizing TURBT

      Wassim (Wes) Kassouf, MD
      McGill University

      8:30 AMUse of Fiducial Markers

      Girish Kulkarni, MD, PhD
      University of Toronto

      8:45 AMNeed for Re-TURBT/Biopsy during Follow-up

      Adam S. Feldman, MD
      Massachusetts General Hospital

      9:00 AMRadical Cystectomy and Diversion Options after Failed RT to Bladder

      Trinity Bivalacqua, MD, PhD
      Johns Hopkins University

      9:15 AMBladder Preservation in Advanced Disease

      TBD

      9:30 AMPanel Discussion and Q&A 
      9:50 AMBreak 
      10:05 AMSession 3: Systemic Therapy Issues - Moderator's Introduction

      Moderator:
      Andrea Apolo, MD
      National Cancer Institute

      10:10 AMChemotherapy: Neoadjuvant vs Concomitant

      Srikala (Kala) Sridhar, MD, MSc, FRCPC
      University of Toronto

      10:25 AMCisplatin-ineligible

      Pooja Ghatalia, MD
      Fox Chase Cancer Center

      10:40 AMCheckpoint Blockade

      Parminder Singh, MD
      Mayo Clinic

      10:55 AMDefinitive Chemotherapy as a Bladder Sparing Strategy for Muscle-Invasive Bladder Cancer

      Gopa Iyer, MD
      Memorial Sloan Kettering Cancer Center

      11:10 AMImmunotherapy: Current Advances through Combination

      Joaquim Bellmunt, MD
      Beth Israel Deaconess Medical Center

      11:25 AMPanel Discussion and Q&A 
      11:45 AMLunch 
      12:45 PMSession 4: Translational Science - Moderator's Introduction

      Moderator:
      Kent Mouw, MD, PhD
      Dana Farber Cancer Center

      12:55 PMKEYNOTE: Science Behind the Abscopal Effect

      Charles Drake, MD, PhD
      Columbia University Medical Center

      1:40 PMTargeting Hypoxia

      Catharine West, PhD
      University of Manchester, UK

      2:05 PMBiomarkers: Transcriptomics

      David Miyamoto, MD, PhD
      Massachusetts General Hospital

      2:20 PMBladder Preservation

      Jason Efstathiou, MD, DPhil
      Massachusetts General Hospital

      2:40 PMPanel Discussion and Q&A 
      3:00 PMClosing Discussion, Looking Ahead 
      3:10 PMAdjourn Meeting 
      Johns Hopkins Hospital, Koch Cancer Research Building, Albert H. Owens Auditorium
      1550 Orleans Street
      Baltimore, MD 21287
      United States

      Travel

      Meeting attendees are welcome to book hotel accommodations according to their preference. The following hotel options will offer convenient shuttle service to/from the meeting location:

      Hilton Garden Inn Baltimore Inner Harbor
      625 S President St.
      Baltimore, MD 21202
      The AUA will provide a shuttle to Johns Hopkins Medical Campus for meeting attendees who stay at the Hilton Garden Inn Inner Harbor.

      Admiral Fell Inn
      888 S Broadway
      Baltimore, MD 21231
      The Admiral Fell Inn provides free shuttle service to Johns Hopkins Medical Campus.

      CME accreditation is currently under review.

      Available Credit

      Accreditation Period

      Course opens: 
      12/02/2019
      Course expires: 
      03/07/2023

      Price

      Price:
      $250.00
      Please login or register to take this course.

      Course Registration Fees

      The registration deadline is February 24, 2020.

       AUA MemberNon-Member
      MD/Urologist$200$250
      PhD Research Scientist$200$250
      Resident, Fellow, Trainee, or Student$150$175
      Industry Representative*$450$450

      *For exhibit/promotional opportunities, please contact Keith Price at kprice@AUAnet.org or at 410-689-3749.

      Cancellation Policy

      Cancellation requests must be made in writing prior to February 24, 2020. Requests may be made via email to customerservice@auanet.org or fax to 410-689-3912. Please call 1-800-908-9414 or email registration@AUAnet.org with any questions related to registration.

      Participant Information & Policies

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      Reproduction Permission: Reproduction of written materials developed for this AUA course is prohibited without the written permission from individual authors and the American Urological Association.

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