Incorporating Genomic Testing for Prostate Cancer into Your Practice Webcast (2022)

There are multiple genomic tests currently available for men to detect and risk stratify prostate cancer. The outcomes of these tests may lead to different detection strategies (observation, immediate biopsy, magnetic resonance imaging [MRI] etc.) and treatment decisions (active surveillance, surgery, radiation, adjuvant therapy etc). We will also discuss germline testing as inherited mutations have considerable implications for screening, treatment, genetic counseling and cascade testing of family members. The availability and marketing of genomic testing has outpaced a reflective, evidence-based medicine approach to using these tests. Discussing the research studies that led to the approval of the various genomic tests, understanding the prognostic clinical endpoints they predict, reviewing current AUA and National Comprehensive Cancer Network® (NCCN®) guidelines for prostate cancer genomic testing, examining available validation studies and utilizing case-based scenarios will provide participants with the knowledge to assess these tests and apply them to their clinical practice.

ACKNOWLEDGEMENTS

Support provided by independent educational grants from:

Astellas
AstraZeneca
Exact Sciences
Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC
Lantheus Medical Imaging
Merck & Co., Inc.
Pfizer, Inc.
Sanofi Genzyme

Target Audience

  • Urologists
  • Residents

Learning Objectives

At the conclusion of this course, participants will be able to:

  1. Discuss the research studies that led to the approval of genomic testing for prostate cancer
  2. Order appropriate genomic testing based on a patient's unique clinical situation
  3. State the NCCN and AUA guidelines for genomic testing for prostate cancer
  4. Discern the different prognostic clinical endpoints provided by various genomic tests
  5. Recognize candidates for, and implications of, germline testing for prostate cancer
Course summary
Available credit: 
  • 2.00 AMA PRA Category 1 Credit™
  • 2.00 Non-Physician Participation
Course opens: 
05/18/2022
Course expires: 
05/18/2023
Rating: 
0

Education Council Disclosures

 Education Council Disclosures 2021

COI Review Work Group Disclosures

 COI Review Work Group Disclosures 2021

All relevant financial relationships have been mitigated. 

AUA Office of Education Staff has nothing to disclose.

Course Director(s)

Joseph Wagner, MD

has a financial relationship (Consultant or Advisor (Robotic Surgery)) with Covidien;.
has a financial relationship (Meeting Participant or Lecturer (Oncology)) with Decipher Biosciences;.
has a financial relationship (Meeting Participant or Lecturer (Oncology)) with Genomic Health;.
Faculty(s)

Matthew Cooperberg, MD

has a financial relationship (Consultant or Advisor (Oncology)) with Exact Sciences;.
has a financial relationship (Consultant or Advisor (Oncology)) with Janssen;.
has a financial relationship (Consultant or Advisor (Oncology)) with Verana Health;.
has a financial relationship (Consultant or Advisor (Specialty Not Specified)) with Astellas;.
has a financial relationship (Consultant or Advisor (Oncology)) with Foundation Medicine;.
has a financial relationship (Consultant or Advisor (Specialty Not Specified)) with Dendreon;.
has a financial relationship (Consultant or Advisor (Oncology)) with Decipher Biosciences;.
has a financial relationship (Scientific Study or Trial (Specialty Not Specified)) with Astra Zeneca;.

Daniel Lin, MD

has a financial relationship (Other) with NIH/NCI;.
has a financial relationship (Other) with Genomic Health, Inc.;.
has a financial relationship (Other) with Department of Defense;.
has a financial relationship (Independent contractor) with Clovis Oncology;.
has a financial relationship (Other) with MagForce USA;.

David Penson, MD

has no relevant financial relationships to disclose at this time.

METHOD OF PARTICIPATION: 

Learners will participate in this online educational activity by viewing the webcast, completing the post-test and evaluation. To claim CME credit for this enduring material, learners must complete the post-test, passing with 80% accuracy, and submit the program evaluation.

Estimated time to complete this activity: 2.00 hours

Release Date: May, 2022
Expiration Date: May, 2023

ACCREDIDATION:

The American Urological Association (AUA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION:

The American Urological Association designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

OTHER LEARNERS:

The AUA is not accredited to offer credit to participants who are not MDs or DOs. However, the AUA will issue documentation of participation that states that the activity was certified for AMA PRA Category 1 Credit™.

EVIDENCE BASED CONTENT:

It is the policy of the AUA to ensure that the content contained in this CME activity is valid, fair, balanced, scientifically rigorous, and free of commercial bias.

AUA DISCLOSURE POLICY:

All persons in a position to control the content of an educational activity (i.e., activity planners, presenters, authors) are required to disclose to the provider all financial relationships with any commercial interest during the previous 24 months. The AUA must determine if the individual’s relationships may influence the educational content and mitigate any conflicts of interest prior to the commencement of the educational activity. The intent of this disclosure is not to prevent individuals with relevant financial relationships from participating, but rather to provide learners information with which they can make their own judgments.

MITIGATION OF IDENTIFIED CONFLICT OF INTEREST:

All disclosures will be reviewed by the AUA Conflict of Interest (COI) Review Work Group Chair and/or Vice Chair for identification of conflicts of interest. The AUA COI Review Work Group, working with Office of Education staff, will document the mechanism(s) for management and mitigation of the conflict of interest and final approval of the activity will be documented prior to implementation. Any of the mechanisms below can/will be used to mitigate conflict of interest:

  • Peer review for valid, evidence-based content by the AUA COI Review Work Group. 
  • Attestation that clinical recommendations are evidence-based and free of commercial bias.
  • Introduction of a debate format (point-counterpoint)
  • Inclusion of moderated panel discussion with unbiased moderator
  • Publication of a parallel or rebuttal article for an article that is felt to be biased
  • Divestiture of the relationship by faculty
  • Recusal from controlling relevant aspects of planning 
  • Selection of alternative faculty for specific topic

OFF-LABEL OR UNAPPROVED USE OF DRUGS OR DEVICES: 

The audience is advised that this continuing medical education activity may contain reference(s) to off-label or unapproved uses of drugs or devices. Please consult the prescribing information for full disclosure of approved uses.


AUA PARTICIPANT INFORMATION & POLICIES

DISCLAIMER:

 The opinions and recommendations expressed by faculty, authors and other experts whose input is included in this program are their own and do not necessarily represent the viewpoint of the AUA.

CONSENT TO USE OF PHOTOGRAPHIC IMAGES:

Attendance at or participation in AUA meetings and other activities constitutes an agreement by the registrant to AUA's use and distribution (both now and in the future) of the attendee's image or voice in photographs and electronic reproductions of such meetings and activities.

AUDIO, VIDEO AND PHOTOGRAPHIC EQUIPMENT:

The use of audio, video and other photographic recording equipment by attendees is prohibited inside AUA meeting rooms.

REPRODUCTION PERMISSION:

Reproduction of written materials developed for this AUA course is prohibited without the written permission from individual authors and the American Urological Association.

SPECIAL ASSISTANCE/ DIETARY NEEDS:

The AUA complies with the Americans with Disabilities Act §12112(a). If any participant is in need of special assistance or has any dietary restrictions, please see the registration desk.

Available Credit

  • 2.00 AMA PRA Category 1 Credit™
  • 2.00 Non-Physician Participation
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