V8-08: Purely off-clamp robotic partial nephrectomy
The negative impact of ischemia on renal function (RF) has led surgeons to develop minimally ischemic techniques to perform partial nephrectomy (PN). The aim of this video is to describe our surgical technique and report perioperative, 3-yr oncologic and functional outcomes of a single centre series of 308 patients treated with robotic off-clamp PN (OFF-RPN).
A prospective renal cancer database was queried and data of all patients treated with OFF-RPN between 2010 and 2015 in a high-volume centre were collected. _x000D_ Patients were placed in an extended flank position and a 5-port access with a side docking was performed. Hilar vessels were not clamped in any case; pure tumour enucleation or enucleoresection were the resection techniques used; renorraphy was omitted for small and exophytic masses and minimized with a “point specific haemostasis” for hilar tumours. _x000D_ Perioperative complications, 3-yr oncologic and functional outcomes were reported. Univariable and multivariable analyses were performed to identify independent predictors of RF deterioration._x000D_
Out of 308 patients treated, 41 (13.3%) experienced perioperative complications, 2.9% of which were Clavien grade ?3. Three-yr local recurrence free survival and renal cell carcinoma specific survival rates were 99.5% and 97.9%, respectively._x000D_ No patient with preoperative CKD-stage ?3B developed severe RF deterioration (CKD-stage 4) at 1-yr follow-up._x000D_ At multivariable analysis, preoperative eGFR (p=0.005) was the only independent predictor of a new onset CKD-stage ?3 in patients with preoperative CKD-stages 1 or 2._x000D_
OFF-RPN is a safe surgical approach in tertiary referral centres, with adequate oncological outcomes and negligible impact on RF.