Increasing rate of non-interventional treatment management in localized prostate cancer candidates for active surveillance
The rate of non-interventional treatment (NIT) in prostate cancer (PCa) active surveillance (AS) candidates were shown to be on the rise. However, contemporary data are unavailable. To address this void, we examined NIT rate in AS candidates between 2010-2014, within 16 Surveillance Epidemiology and End Results (SEER) registries.
We identified 23,360 PCa patients that fulfilled the University of California, San Francisco AS criteria (prostate specific antigen [PSA]
Between 2010-2014, NIT rate increased from 30.2 to 57.5% (p=0.004). Within 16 SEER-registries, NIT rates ranged from 25.9 to 62%. NIT rate increased uniformly within all examined registries. Of patient and tumour characteristics (PSA >4ng/ml, cT2a and >1 positive core) only the proportion of NIT patients aged
The rate of NIT as markedly increased across all examined SEER-registries. Nonetheless, very important differences distinguish high-end NIT users from low-end NIT users. PCa characteristics of NIT patients remained unchanged overtime. However, in addition to geographical differences in NIT rates, patient characteristic such as age, marital and insurance status represent potential NIT access barriers.