MP14-14: Propensity Score Matched Study to Examine the Ef ... ough Magnetic Resonance Imaging of the Prostate

Propensity Score Matched Study to Examine the Effect of Race on the Number of Lesions Suspicious for Prostate Cancer Detected Through Magnetic Resonance Imaging of the Prostate

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INTRODUCTION

The difference in the characteristics of clinically significant lesions on mpMRI of the prostate between black and white men is not well examined. The aim of this study was toevaluate the effect of race on dimensions, location, PIRAD score, and the number of such lesions.

METHODS

An institutional retrospective study of all patients who received a prostate MRI between the years 2015 and 2017 was performed to detect any lesions in the prostate for screening, staging or following up as active surveillance. Number of prostate lesions (0 - 4), the location, dimensions of the lesion, and the PIRAD score v2 was evaluated. A matched cohort of white and black patient was developed using propensity score matching on age, PSA scores, and prostate volume. Comparisons between the two groups was preformed using chi-squared test, p

RESULTS

592 patients had prostate MRIs performed between 2015 and 2017,141 black patients were matched with equal number of white men with similar characteristics. The black population mean age was 63 years (±SD 9.36), PSA 9.45 (±SD 9.57), and prostate volume 71 g (±SD 53.65). The white population mean age was 63 (±SD 7.92), PSA mean 8.63 (±SD 8.39), and Prostate volume mean 63 (±SD 42.11). The number of lesions was 2 or more in 26% of black men and 12% of white men (P=0.0025), and 3 or more in 10% of black and 2% of white men (P=0.001). There was no significant difference in PIRADS scores, location or dimension of the lesions between the two groups.

CONCLUSION

Black patients, as compared to white counterparts, have a higher number of lesions detected on prostate mpMRI. The other characteristics of MRI detected prostate lesions were similar between the two groups.

Funding: None