The PRIME framework for investigating emotions and other patient factors in low-intermediate risk prostate cancer patients based on online cancer support group discussions
To use the Patient Reported Information Multidimensional Exploration (PRIME) framework, a novel ensemble of machine learning and deep learning algorithms, to extract, analyse and correlate self-reported information from online support group discussions (OCSG) by patients (and partners of patients) with low-intermediate risk PCa undergoing radical prostatectomy (RP), external beam radiotherapy (EBRT) and active surveillance (AS), and investigate its efficacy in determining Quality of life (QOL) and emotion measures.
All discussions related to low-intermediate risk PCa were extracted from ten OCSG with active user participation. A total of 390,071 online discussions by 6084 patients were analysed using the PRIME framework. Side effects and emotional/QoL outcomes were analysed.
Side effect profiles differed between the modalities analysed, with men post-RP having more urinary and sexual side effects and men post-EBRT having more bowel symptoms. Key findings from the analysis of expressions of emotion; (i) PCa patients aged