The adverse risk factors of urinary function recovery after radical prostatectomy
To investigate the adverse risk factors of urinary function recovery after radical prostatectomy
The surgical database of 126 patients treated with laparoscopic radical prostatectomy between October 2015 and October 2016 were collected and analyzed retrospectively. The mean age is 70 years (48-85 years). BMI 16.8-24.7 kg/m2, mean 24.6 kg/m2 ; PSA 1.73-274.5μg/L, mean 25.9μg/L; PSA≤10μg/L 55 cases (43.7%). 10-20μg/L 31 cases (24.6%); ≥20μg/L 40 cases (31.7%); Gleason score ≤6 im 13 cases (10.3%); score 7 in 42 cases (33.3%); score ≥8 in 71 cases (56.4%); T2a in 16 cases (12.7%), T2b in 20 cases (15.8%), T2c in 67 cases (53.2%), T3a in 23 cases (18.3%); positive surgical margins in 0 cases. All patients were followed up for 24-48 weeks, observing for leakage after surgery, the number of urine pads used per day, time when less than one pad was used per day, and frequency of kegel exercises.
The pathological results were prostatic adenocarcinoma. The overall recovery of continence 12 weeks after surgery was 46.8% (59/126) and was 88.1% (111/126) 24 weeks after surgery. In a univariate logistic regression test, age (P=0.034), BMI (P=0.044), and nerve sparing (P=0.005) were associated with recovery of urinary continence within 12 weeks after surgery (P<0.05). In multivariate logistic regression analysis, age (P=0.011), BMI (P=0.022) and nerve sparing (P=0.014) were independent factors that each predicted the recovery of continence within 12 weeks after surgery (P<0.05).</p>
Younger age, lower BMI, and intraoperative nerve sparing independently predicted the recovery of continence within 12 weeks. Age is the sole influencing factor of continence recovery within 24 weeks.